مسار بولونيا
AR
Research Nawal Mustafa Abdullah Al shannan
A retrospective descriptive study of emergency presentation and surgical management of colorectal cancer
2025 Romanian medical journal
Background and objectives. Colorectal cancer (CRC) is one of the leading causes of cancer-related death in Iraq, where no nationwide screening programs exist. Data on emergency presentations and surgical outcomes are limited. This study aimed to describe the clinical manifestations and surgical management of colorectal cancer in patients presenting emergently in Basrah, southern Iraq. Patients and methods. Between September 2021 and September 2023, 37 patients were identified from 300 colorectal cancer cases admitted to Al-Sadr Teaching Hospital and Basrah Oncology Center. Patients presented with acute symptoms, including intestinal obstruction, perforation, rectal bleeding, anemia, and generalized weakness. All underwent diagnostic evaluation, including colonoscopy, tumor markers, and imaging. Surgical and oncological management were recorded. Results. Of 37 patients, 23 were male (62.2%) and 14 female (37.8%). The most common presentation was partial intestinal obstruction (46%), followed by complete obstruction (13.5%), perforation (13.5%), and rectal bleeding (13.5%). Adenocarcinoma and mucinous adenocarcinoma were the predominant histological subtypes. Surgical resection with primary anastomosis was performed in 24 patients, resection with colostomy in 5, and resection with double stomas in 2. Two patients were deemed inoperable, 2 refused surgery and received neoadjuvant chemoradiotherapy, and 2 declined all treatment. Conclusion. Emergency presentation of colorectal cancer remains common in Basrah, reflecting delays in diagnosis and the absence of systematic screening. Implementation of early detection and population-based screening strategies is essential to reduce emergency admissions and improve outcomes.
COMPARATIVE STUDY BETWEEN OPTIMAL AND REDUCED FORMALIN-BASED FIXATIVE FOR NORMAL AND PATHOLOGICAL TISSUES
2020 Asian J Pharm Clin Res
Objectives: This study aims to use an alternative fixative compound with reduced concentration of formalin to minimize the exposure and related side effects. Methods: Human normal and pathological tissue samples of different organs were immediately immersed in a modified fixative containing formalin, glycerin, ethanol, and hypotonic saline with pH around 7. Two time schedules were used at 8 and 12 h. Tissue samples were undergone routine processing procedure used in histopathological laboratories, scoring of samples was done, tissue sections of new compound fixative were examined for cytoplasmic, nuclear, and architectural properties and compared with 10% neutral buffered formalin (NBF). Results: Tissue samples treated with modified fixative showed good and acceptable preservation of structural, cellular details with less harmful effects when compared with those preserved with routine 10% (NBF). Conclusion: The suitability and effectiveness of reduced formalin-based fixative in histological and histopathological routine examination with minimal harmful effects for laboratory worker were clearly indicated in this study. Keywords: Formalin, New fixative, Histopathology, Tissue sections.
Intervertebral disc herniation (Schmorals nodes ) of thoracic and lumbar spine : A study of prevalence ,characterization and correlation with osteophytes changes
2005 Basrah J of Surgery
The profile of congenital and hereditary urinary tract disorders in patients presented to Saddam teaching hospital
2001 Basrah J of Surgery
Fingerprints distribution in Basrah with pattern of inheritance of right and left indices
2000 Basrah J Of Science
The effect of inbreeding on resorption weight and numberof aliveimplants up to day 18of pregnancy in mice
2000 The Medical Journal Of Basrah University
Histological changes of mice skin in protein energy malnutrition
2003 Tikrit medical journal
Histological study on the effect of chronic maternal protein malnutrion on the mice placenta
2003 The medical j of Basrah university
The Role of Intrauterine Bigatti Shaver in Removal of Retained Products of Conception in Sample of Iraqi Women
2025 Journal of Obstetrics, Gynecology and Cancer Research
Background & Objective: Intrauterine Bigatti shaver has several benefits over classical methods like dilation and curettage. It offers a more precise tissue removal, facilitating improved visualization to the uterine lining .This procedure is deemed safer, and consumes less time and effort. To highlight the effectiveness of the Bigatti Shaver as a valuable treatment option particularly in patients with miscarriages or complicated dilatation and curettage. Materials & Methods: Fifty women aged between 18-44 years underwent placental remnant removal using Bigatti Shaver. The primary outcomes include complete removal of retained products of conception (RPOC), procedure time and possible complications while secondary outcomes focused on patient satisfaction and necessity for further intervention. Results: The Bigatti Shaver demonstrates remarkable success in completely removing RPOC in all 50 women (100%). The size of placental remnants varied between 15-33 mm. The resection time has a range of 22-110 seconds. Results showed a positive correlation between age and size (r=0.552), age and resection time (r=0.331) .additionally size and resection time (r=0.559), size and infection (r=0.415) and time and infection (r=0.470). Follow up of postoperative patients revealed mild infection in two and mild vaginal bleeding in 4 patients. Conclusion: The Bigatti Shaver (IBS) is confirmed to be a safe and effective procedure for the removal of RPOC. Overall, patient satisfaction was highly encouraging. Keywords: Retained products of conception, Intrauterine Bigatti Shaver
Evaluation of Electromagnetic Therapy in the Treatment of Severe Dysmenorrhea in Young Women of Basrah
2024 Annals of African Medicine
Introduction: Primary dysmenorrhea (PD) is a public disease of young female worldwide, it affects their daily performances. Severe recurrent uterine cramps are the main complaints in 90% of adolescents and 50% of reproductive‑age females. This study aimed to evaluate the use of magnetic field therapy in the treatment of severe dysmenorrhea grade 3 and provide an encouraging goal to continue daily work without pain. Methods: Two hundred and fifty female patients were recruited in this study from gynecological clinics in Basrah, southern Iraq. All had severe dysmenorrhea, patients were subjected to a questionnaire form, Visual Analog Scale, and verbal multidimensional scoring system to determine the pain intensity and grade of dysmenorrhea. Only 38 young females had severe dysmenorrhea grade 3 with ages ranging from 16 to 28 years with a mean age of 22.04 ± 1.43 years and body mass index 23.81 ± 1.94, patients subjected to electromagnetic field therapy (EMFT), two sessions per week for 20 min each for 6 weeks. Three categories were assessed, working ability, associated symptoms, and drugs used. Data were collected and statistically analyzed using SPSS version 22. Results: The present study showed statistically significant progress (P < 0.05) in reducing pain, rare physical and mental complaints, and improved working ability with no need for drugs in majority of patients. Conclusion: EMFT has better results than other methods in relieving pain and symptoms of dysmenorrhea with a settled lifestyle. Keywords: Electromagnetic therapy, primary severe dysmenorrhea, women
Revision of Gastric Plication to Gastric Bypass (Indications and Solutions)
2022 Macedonian Journal of Medical Sciences
BACKGROUND: Laparoscopic gastric plication (LGP) has gained increased acceptance as initial weight loss operation, but as with any other procedures, insufficient weight loss, early and late complications such as early and late strictures, gastroesophageal reflux and leak and others have been announced as an indication for revision to gastric bypass surgery as the correct solution. AIM: The aim of the study was to recognize the common indications for revision of gastric plication (GP) to RYGP and OAGB in our centers and to evaluate the outcome of treating weight regain, complications, and comorbidities. METHODS: A retrospective study conducted on 54 cases of undesirable results following gastric plication in other centers that were revised to gastric bypass procedures (RYGB and OAGB) from June 2015 to June 2018. Weight regain, gastroesophageal reflux disease not responding to medical treatment, undiagnosed hiatal hernia at surgery, post-operative leak, and strictures are the main categories included as indications for revision to gastric bypass in this study for a period of follow up to 2–5 years regarding weight loss, improvement of GERD and hiatal hernia, improvement of leak, stricture, and axial rotation of stomach. RESULTS: 54 consecutive patients included in this study previously subjected for LPG few years ago. 13 (24%) male and 41 (76%) female patients with mean age of 39.5 years ranging from (21–58) years and BMI from (41–48) Kg/m2. The main indication for revision surgery in the form of gastric bypass procedure (RYGB and OAGB) was weight regain in about 69% of cases. In addition to non-responding GERD to medical treatment (13%), hiatus hernia with plicated stomach migration to the mediastinum (3.7%), local collection secondary to leak (1.85%), stricture at site of plication (1.85%), and one case of axial rotation of the stomach (1.85%). Patient postoperatively done well and a follow-up for up to 3 years after revision surgery was uneventful. Most of our patients have good improvement regarding the inclusion criteria in our study (100% cured GERD, 90% cured leak site, about 90% cured symptomatic and radiological hiatal hernia, 100% cured after early, late strictures, and axial rotation while regarding loss of weight and least comorbidities about 88%). CONCLUSION: Although GP is an established bariatric procedure in treating and solving obesity and its complications, there are certain restrictions and difficulties that makes RYGB superior to GP.
Perineural invasion in nearby tissue adjacent to colorectal carcinoma with CD166 stem cell marker expression
2023 Current Issues in Pharmacy and Medical Sciences
Pathological evaluation of colorectal cancer resection samples play a vital role in management and prognosis of postoperative cancer patients. Difficulties exist in the assessment and outcomes of these specimens for therapy protocol. PNI is a perineural invasion associated with increased mortality in many malignancies including colon cancer. In colorectal cancer (CRC) and nearby tissue, PNI evaluation as a potential prognostic indicator with the use of CD 166 stem cell marker remains to be clearly defined for providing a convenient information for future management and prognosis. T he incidence and significance of histological neural invasion in nearby tissue was conducted in 52 patients with colorectal carcinoma operated on for the period from June 2017 to June 2020 retrospectively. Tumors were subjected to histopathological and immunohistochemical study (IHC) with CD166 stem cell marker for PNI in tissue adjacent to CRC. Data collected and analyzed, histopathological pictures was obtained and studied. Outcomes showed that neural invasion was expressed by Cd166 stem cell marker as strong and severe in patients with stage B and C in tissues nearby tumor which reveals bad prognostic features. Conclusions: Neurogenesis appeared to have a critical role in colorectal cancer progression. furthermore, current results indicated that neurogenesis functions as an independent predictor of outcomes for therapy protocol
Effect of Blood Groups and Complications on Orofacial Measurements of B Thalassemia Adult Patients
2021 Medico-legal Update
Background: β- thalassaemia is a common hereditary disorders in Iraq and worldwide .with different treatment schemes,, including blood transfusion, iron chelation and splenectomy, patients with B thalassemia may develop different skeletal changes. Limited studies link these complications with orofacial changes, This study aimed to evaluate the orofacial dimensions in β- thalassemia patients with age, gender, blood groups, splenectomy and cholecystectomy and to assist surgeons for planning their future intervention. Method: This study was conducted on 130 ß-thalassemia patients of both gender,,and two age categories (20 30 yrs), & (21-40 yrs), five orofacial measurements (face,eyes,nose,mouth and ears) and sixteen parameters were measured and calculated for differences,P value is estimated,data analysis were done by using Chi square test and SPSS version 20 Results: Significant findings were found for mandibular width and mouth width at older age group (31-40 years), the nasal width and ear height are more in male, patients with splenectomy have significance for lower 1\3 face and ear width. Cholecystectomy increase eye length measurments and ear height but for blood groups the P ˃ 0.05 Conclusions: Orofacial bone changes are pronounced in β- thalassaemia with distinct findings regarding sex dimorphism, older are more prone to have variations, earlier splenectomy is advisable,cholecystectomy is better choice for symptomatic patients, blood groups have no significance. Keywords: βThalassemia,,Blood groups, Orofacial measurments, Complications
Comparable study of expression of CD44, CD166 and ALDH1A1 markers in normal tissue adjacent to mucinous and non-mucinous adenocolorectal carcinoma in sample of Iraqi patients
2017 International Journal of Medical Science and Clinical Inventions
Abstract Background: Colorectal cancer is one of the commonest malignant tumors among men and women worldwide with large morbidity and mortality 90% of colorectal carcinoma are adenocarcinoma while mucinous type comprising >20% of all colorectal cancers . Development process is slowly with late diagnosis, therefore early detection and screening is of vital importance. CD44, CD166 and ALDH1A1 are stem cell markers with different expressions depending on type of tumor and relation to clinical parameters. Objective: To highlight expression of CD44,CD166 and ALDH1A1 in normal tissue adjacent to mucinous and non-mucinous colorectal adenocarcinoma and correlate with clinic- pathological parameters in a group of Iraqi patients. Methods: A retrospective study of 70 cases with normal tissue adjacent to colorectal carcinoma obtained from two hospitals from 2015 to 2016, divided into two groups. Paraffin blocks were IHC treated with CD44, CD166 and ALDH1A1 markers to compare the expression pattern of these stem cell markers. Results: The study revealed that 15.7 % were mucinous CRC with mean age 59yrs and equal M / F ratio and common site is rectum and recto sigmoidal region .CD44 CD166 and ALDH1A1 markers had different expression pattern among mucinous and non-mucinous CRC. Conclusion: The normal tissue adjacent to CRC had different marker expression properties depending on type of the tumor. Key Words: CRC, CD44, CD166 and ALDH1A! Markers and IHC
IMMUNOHISTOCHEMICAL EXPRESSION OF STEM CELL MARKERS CD44, CD166 AND ALDH1A1 IN NON NEOPLASTIC POLYPS OF THE COLON IN SAMPLE OF IRAQI PATIENTS
2017 Basrah Journal Of surgery
The aim of this retrospective study on tissue specimens of benign colorectal polyps is to evaluate the significance of IHC markers CD44, CD 166 and ALDH1A1 expression in non-neoplastic (Juvenile and Hamartomatous) polyps and their association with different clinicopathological parameters & to compare their expression in benign polyps with that of normal colonic tissue . Seventy cases enrolled in the study including benign polyps (juvenile & hamartomous polyps) & benign looking colonic tissue obtained from archive of histopathology unit in Gastroenterology and Hepatology hospital in Baghdad Medical City and histopathology unit in Al-Sadder Teaching Hospital in Basrah city for the period Sept. 2015 to Dec. 2016. Four micrometer sections were obtained from formalin fixed paraffin-embedded blocks treated IHC with CD44, CD166 and ALDH1A1 tumor markers. Majority of polyps were juvenile, no difference regarding gender distribution. The common location was rectum/rectosigmoidal region. CD166, CD44 and ALDH1A1 showed high expression regarding age, gender and location in benign tumors when compared with healthy looking tissue. In conclusion, colorectal polyps are critical clinical entity and many of them are a precursors to malignant diseases so colonoscopy is essential screening test, polypectomy and follow up is mandatory for patients with colorectal polyps even if they are benign.
ANTHROPOMETRIC MEASUREMENTS OF HUMAN FACE IN BASRAH
2014 Basrah Journal Of Surgery
Abstract Anthropometry is the systematic quantitative representation of the human body, it is used to measure the absolute and relative variability in size and shape of the human body. Over the centuries, there have been remarkable changes in anthropometric measurements due to geographical, cultural, genetic and environmental factors. The studying of human face and the assessment of facial dimensions attract the attention of the artists, poets and scientists and takes a prime importance in medical and dental fields in both diagnosis and treatment planning. Anthropometry also used for the design of clothing and equipment, e.g. Gas masks, oxygen masks, dust masks and respirators as well as design of military and industrial helmets. There had been no studies done on facial measurement in Basrah therefore, this study is to be considered as the first in this field and the baseline for further studies. This study had attempted to quantitatively measure the human face in different ethnic groups of the local population and to identify the differences between individuals of different races and sexes, also to identify the differences between the people of Basrah and other people worldwide. These differences which are responsible for the special facial features in different ethnic groups should be maintained during reconstructive or aesthetic surgery otherwise the patients will lose their ethnic features. The people of Basrah have different racial and ethnic background, there are Semites which are the Arabs and Syrian (Assyrian & Chaldean), Arian, who are the Armenian, Kurdish and Persian, and then there is the mixed group result from interracial marriages. This study is a cross sectional study with a comparative component conducted in Basrah governorate. The data was randomly collected from volunteers, for the period from February to July 2013. Raw data used in this study was originated from a total number of 1000 Iraqi adults (526 females and 474 males) living throughout Basrah governorate and were used to create a database for statistical analysis. The result of this study shows that there are differences between the races and between the local people and the surrounding countries and indeed there is a great difference from the standard measurement advocated by western researchers.
Variability of Vertical and Horizental Facial Measurments Among The Population Of Basrah
2016 The Iraqi Postgraduate Journal
A Cadaveric Study on the Prevalence of Hartmann Pouch of Gallbladder with Relation to Gallstones in Basrah City
2020 Indian Journal of Forensic Medicine & Toxicology
Hartmann pouch is a dilatation of the wall of the gallbladder at the region between neck and the cystic duct, It is inconstant feature found as an anatomical variant and considered a frequent site for gall stone impaction and mucocele formation as a complication . Knowledge about anatomy of the pouch is important while performing surgery for cholecystectomy to avoid serious complications. Objective: To identify the incidence and nature of Hartmann’s pouch in human gallbladder and the relation with gallstones for the growing importance and use of various invasive surgical techniques for gallbladder and extrahepatic biliary diseases. Material and Method: The study was carried out in the department of Forensic Medicine at Basrah city ,from Jan 2018 to Jan 2019 .Two hundred fourteen gallbladders were obtained from cadavers that were under examination in the morgue , The gallbladders were examined morphologically to show Hartman pouch and gall stone existence and biopsies from the pouch were taken for histopathological examination. Results: In the present study Hartman pouch was found in 4.7%, usually at older age group (˃ 40 yrs.). It was slightly higher in male than female and no significant association between Hartman pouch and gall stone presence. Histological picture showed normal histology of the three layers as seen in normal gallbladder Conclusion: Hartman pouch is inconstant feature, more in male with no significant relation to gall stone, exist as an anatomical entity in our area of study. Key words: Hartmann pouch, gallstones and percentage
Ventricular False Tendons in Human Hearts, An Autopsy Study of the Incidence, Morphology, Histology, and Distribution in Basrah City
2019 Biomedical & Pharmacology Journal
The left ventricular false tendons (LVFTs ) are fibrous or fibromuscular bands crossing the left ventricle in human hearts ,they arise mainly from the ventricular septum to the free wall or to a papillary muscle .They are considered as normal anatomical variant with different numbers, location and type. LVFTs had been associated with many clinical studies and discussions regarding their function . Literatures were reviewed and their incidence ,morphology , histology and clinical correlation were discussed .This study was intended to evaluate the existence LVFTs in Basrah city , and to compare the findings with other data verified in literatures. A prospective autopsy study of the prevalence and morphology of LVFTs in 215 cadaveric human hearts was performed to estimate the number ,types and location .of these bands .10 out of 215 samples were undergo routine histopathological processing to obtain 4 micrometer thickness slides stained with hematoxylin and eosin and examined for histological characteristics . LVFTs of varying number, types and different attachment were recorded in 62 ( 28.8% ) of 215 adult human cadaveric hearts studied. A complete morphologic assessments were done. No significant differences was found regarding age or gender. , Majority of LVFTs are single , commonly between the ventricular septum and papillary muscle .Fibrous and fibro muscular type is predominant . In our community false tendons are frequent anatomic variants of normal human LV which may be identified at routine examination and should not be mistaken as pathologic structures such as flail chordae tendineae or thrombi, further radiological and clinical studies are suggested to ensure their role and function .
Angiographic anatomical variation of origin of left circumflex coronary artery in Basrah
2017 THE MEDICAL JOURNAL OF BASRAH UNIVERSITY
ABSTRACT Background: The left circumflex coronary artery normally originated from left coronary artery , however, this artery may change its origin either from left aortic sinus or from right aortic sinus. This knowledgement may help in understanding some of ischemic heart diseases and its consequences on cardiac surgery. Objective: To know the incidence of anatomical variations of left circumflex coronary artery origin among people in Basrah. Patients and Method: Prospective study of the coronary angiography carried out in cardiac catheterization center at Al-Sader Teaching Hospital during period from 5th of October 2012 to end of June 2013. A sample of 315 patients was recruited with normal coronary angiography. Results: In the present study the left circumflex artery was variable in its origin, the left circumflex artery originated from the left coronary artery in 97.1%, originated from the left aortic sinus in 1.9% and in 1% of the sample it originated from right aortic sinus. Conclusions: Recognition of the origin of left circumflex coronary artery and its anatomical variations before cardiac surgery is important to prevent myocardial infarction and death. Special surgical consideration must perform in valvular replacement in patient with variation of origin of left circumflex coronary artery. Keywords: angiography, anatomical variation.