مسار بولونيا
EN

نسرين جلال محمد فارس

السنة عنوان البحث نشر البحث
2019 5. Wound Healing Properties and Cytotoxicity of Gold Nanoparticles on MDCK cell lines (in Vitro study) ndian Journal of Public Health Research & Developmenti
The research study was aimed to investigate the effect of Gold nanoparticles(AuNPs) at different concentration on the wound healing of Madin-Darby Canine Kidney epithelial normal cell line in comparison with control group. Gold nanoparticles were prepared in chemicals methods with diameter of 23-26nm. The cytotoxic effect of gold nanoparticles was tested on the (MDCK) cells. The AuNP concentrations of (500, 250, 125, 62.5, 32.25)μg/ml inhibit the proliferation of MDCK cells. The enhancement concentration was chosen for this research study. The wound was made on Madin-Darby Canine Kidney epithelial (MDCK) cell lines at diameter of 250 pixel. The wound size was measured at different time every 3hours starting from (12afternoon, 3h, 6h, 9h, 12midnight). The results observed there was a significant decrease (p≤0.001) in the size of wound at the concentration of Au NPs (15.6, 7.8)μg/ml respectively in comparison with control group.