مسار بولونيا
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لمى حكمت كريم البياتي

السنة عنوان البحث نشر البحث
2020 AEROBIC PATHOGENIC BACTERIA PATTERN OF BURN INFECTION AND THEIR ANTIMICROBIAL SUSCEPTIBILITY (2017 TO 2019) IN AL-KUT CITY, IRAQ Biochem. Cell. Arch
Burn wound infection considerable is a major serious problem and one of the most important causes of morbidity and mortality for burn patients, mainly caused by aerobic pathogenic bacteria. Bacterial infections and their antibiotic resistance was a dangerous problem in the correct treatment of burn patients. This study aimed to identify the most prevalent pathogenic aerobic bacteria that causing burn wound infections and detected the antibiotic susceptibility patterns among hospitalized patients; over three years. A cross-sectional study was performed on patients referred to a Burn Center of Al-Zahraa Teaching Hospital in Al-Kut, Iraq over three years (from January 2017 to September 2019). In this study, 160 burns swabs were collected from hospitalized patients with burn wound infections. Specimens of tissue for bacterial culture were collected from burn wounds using standard collection techniques and grown bacterial isolates was done by conventional biochemical tests. The disk diffusion method was performed for testing antibiotic resistance according to CLSI guidelines. The study revealed that the main source of burns was gas flames (51.25%) and scalds (36.25%). Among 160 burn swabs enrolled in the study, 96 patients (60%) were positive culture and 64(40%) were culture-negative for bacteria. Pseudomonas aeruginosa was the most predominant bacteria in patients (48.1%) followed by E.coli (8.7%) but Klebsiella spp. was the least common bacteria with only (3.1%). In the evaluation of antibiotic resistance, all bacterial strains were highly resistant to most Antimicrobials. Although Pseudomonas sp. showed varying resistance levels to a common antibiotic such as Cefaclor (100%), and Cefixime (100%) but, Imipenem and Azithromycin had a better effect than other antibiotics. Based on the obtained results, Pseudomonas aeruginosa constituted the most common bacterial microbes causing burn infection over the three years. Imipenem and Azithromycin are a drug of choice for treatment of these infections. Thus, it is essential to use a careful selection of antibiotics to control the wound infection is required for proper management of burn and to prevent the extension of resistant bacteria to help reduce morbidity and mortality.